 예성수 교수 E-mail : ssyea@inje.ac.kr |
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학력사항 - 연세대학교 이과대학 생화학과 학사 (1994) - 한국과학기술원(KAIST) 생물과학과 석사 (1996) - 한국과학기술원(KAIST) 생물과학과 박사 (2000) |
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경력사항 - 인제대학교 의과대학 생화학교실 주임교수 (2016~현재) - 인제대학교 의과대학 생화학교실 전임강사/조교수/부교수/교수 (2001~현재) - University of California, Irvine, Visiting Associate Researcher (2011~2013) - 인제대학교 백인제기념연구소 연구강사 (2000~2001) - Michigan State University, Visiting Scholar (1997~1998) - 식품의약품안전평가원 독성시험평가 전문위원 (2017~2019) - Journal of Life Science, 편집위원 (2013~현재) - Molecular & Cellular Toxicology 편집위원 (2006~2010) - 환경부 내분비계장애물질 전문위원 (2005~2007) |
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연구분야 - 면역세포 신호전달 연구 - 면역기능조절, 항암면역, 항산화면역 연구 - 화합물의 약리/독성 평가 및 분자세포생물학적 작용기전 규명 |
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주요 연구물
- Secretome profiling of PC3/nKR cells, a novel highly migrating prostate cancer subline derived from PC3 cells. PLoS One 14(8):e0220807 (2019) - A PI3K p110α-selective inhibitor enhances the efficacy of anti-HER2/neu antibody therapy against breast cancer in mice. Oncoimmunol. 7(5):e1421890 (2018) - 3,3'-Diindolylmethane inhibits VEGF expression through the HIF-1a and NF-kB pathways in human retinal pigment epithelial cells under chemical hypoxic conditions. Int. J. Mol. Med. 36:301-308 (2015) - Effects of novel isoform-selective phosphoinositide 3-kinase inhibitors on natural killer cell function. PLOS-ONE 9(6):e99486 (2014). - Caffeic acid phenethyl ester inhibits the inflammatory effects of interleukin-1β in human corneal fibroblasts. Immunopharmacol. Immunotoxicol. 36(5):371-377 (2014) - Achieving cancer cell death with PI3K/mTOR-targeted therapies. Ann. NY Acad. Sci. 1280(1):15-18 (2013) - Selective inhibition of phosphoinositide 3-kinase p110a preserves lymphocyte function. J. Biol. Chem. 288(8):5718-5731 (2013) - New mTOR Targets Grb Attention. Science 332:1270-1271 (2011) - Expression of galectin-9 by IFN-γ stimulated human nasal polyp fibroblasts through MAPK, PI3K, and JAK/STAT signaling pathways. Biochem. Biophys. Res. Commun. 411(2):259-64 (2011) - Cilostazol protects mice against endotoxin shock and attenuates LPS-induced cytokine expression in RAW 264.7 macrophages via MAPK inhibition and NF-kB inactivation: Not involved in cAMP mechanisms. Int. Immunopharmacol. 10:1077-1085 (2010) - Cilostazol is anti-inflammatory in BV2 microglial cells by inactivating nuclear factor-kappaB and mitogen-activated protein kinases. Br. J. Pharmacol. 159(6):1274-1285 (2010) - Alaria esculenta Extract Protects against Oxidative Damage by Inducing Heme Oxygenase-1 Expression via Akt and Nrf2. Mol. Cell. Toxicol. 5(2):120-125 (2009) - Evaluation of anti-allergic properties of caffeic acid phenethyl ester in a murine model of systemic anaphylaxis. Toxicol. Appl. Pharmacol. 226(1):22-29 (2008) - Bisindoylmaleimide I suppresses adipocyte differentiation through stabilization of intracellular β-catenin protein. Biochem. Biophys. Res. Commun. 367:195-200 (2008) - Suppression of interleukin-2 gene expression by isoeugenol is mediated through down-regulation of the NF-AT and NF-kB. Int. Immunopharmacol. 7: 1251-1258 (2007) - Isoeugenol suppression of inducible nitric oxide synthase expression is mediated by down-regulation of NF-kB, ERK1/2, and p38 kinase. Eur. J. Pharmacol. 576:151-159 (2007) |
